30 square metres of hope

The Joint Stem Cell and Immunology Laboratory at Tübingen University Hospital supplies clinics all over the world. Here, in Class A.B and C cleanrooms, stem cell preparations for cellular immunotherapy are processed – in a space measuring just 30 square metres. But they pack a punch! A wide range of highly specialised high-tech equipment (including several CliniMACS Prodigy systems for semi-automated cell processing) enables patient-specific preparation and cultivation of cells. If necessary, the cell preparations can even be cryopreserved, i.e. frozen for later use.

Twice a year, we and our employees are responsible for requalifying the GMP areas within the stem cell and immunology laboratory. And although the cleanroom areas cover ‘only’ about 30 square metres, the requalification measurements take between two and three days. This is due to the scope of the individual parameters that have to be measured in such a sensitive area. Including filter leakage and tightness tests, recovery time, air volume flow, differential pressure, air purity class, and microbiological measurements and tests.

Published: September 2025